Bioequivalence Study with Two Naproxen Sodium Tablet Formulations in Healthy Subjects
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منابع مشابه
Bioequivalence Study with Two Naproxen Sodium Tablet Formulations in Healthy Subjects
The purpose of this study was to find out whether the bioavailability of a 550 mg naproxen sodium (CAS 22204-531 ) tablet (Sunprox, test) produced by Sunward Pharmaceutical Sdn Bhd was equivalent to that produced by the innovator. The pharmacokinetic parameters assessed in this study were area under the plasma concentration-time curve from time zero to 72 hours (AUCt), area under the plasma con...
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AIM To compare the bioavailability of two 40-mg Rosuvastatin tablet formulations. METHODS 24 subjects were included in this single-dose, open-label, randomized, two-way crossover study following an overnight fast. A 2-week wash out period was applied. Blood samples were drawn up to 72 hours following drug administrations. Rosuvastatin plasma concentrations were determined by liquid chromatogr...
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INTRODUCTION The present study was conducted to compare the bioavailability of two candesartan cilexetil 16 mg tablet formulations (test and reference formulations). MATERIALS AND METHODS This study was a randomized, single- blind, two-period, cross-over study which included 24 healthy adult male and female subjects under fasting conditions. The pharmacokinetic parameters were determined base...
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The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...
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The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...
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ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2009
ISSN: 0975-0851
DOI: 10.4172/jbb.1000005